Menu
Perryville, Missouri

Every slice
tells a story
worth savoring.

Hand-tossed. Wood-fired flavor. Built on recipes that don't need updating — just remembering. Salerno's Pizzeria is Perryville's destination for pizza done right.

Call to Order View Menu
5029 US-61, Perryville
Open Today
Freshly baked pizza pulled from a hot oven at Salerno's Pizzeria
Walk-ins Welcome
Delivery Available
Family Owned & Operated
Fresh Ingredients Daily
Pizza chef preparing dough by hand at Salerno's Pizzeria
Pizza baking in a blazing hot oven
Close-up of a freshly sliced pizza with melted cheese
Warm dining room interior at Salerno's Pizzeria
Since
Day One
Our Story

We don't chase trends.
We chase perfection.

Salerno's Pizzeria wasn't born from a marketing team. It was built by people who believe that a great pizza doesn't need a gimmick — it needs good dough, quality toppings, and an oven that runs hot enough to make you forget your name for a minute.

Located right off US-61 in the heart of Perryville, we've been serving our community one pie at a time. Our recipes haven't changed because they didn't need to. The crust is still hand-tossed. The sauce is still made from scratch. And the cheese still stretches exactly the way it should.

Whether you're grabbing a quick dinner or settling in for a family meal, we treat every guest like they're walking into our own kitchen. Because that's exactly where the food comes from.

100%
Fresh, never frozen dough
Daily
Ingredients delivered fresh
Hot
Every single pie, every time
What People Say

Don't take our word for it.

Our best marketing is a full dining room and empty plates. Here's what our regulars keep coming back to tell us.

"Best pizza in the area, hands down. The crust is always perfect — crispy on the outside, soft on the inside. We come here every Friday night without fail."

M
Mike D.
Perryville local

"The atmosphere is so welcoming — feels like home. The staff remembers your name and your order. That kind of place is hard to find anymore."

S
Sarah T.
Regular since opening

"We drove an hour just to try it after hearing about it. Left with leftovers and a promise to come back. The BBQ chicken pie changed my life."

J
Jason R.
Visited from St. Louis
Visit Us

Come hungry.
Leave satisfied.

We're right off US-61 in Perryville — easy to find, impossible to forget. Stop by for a slice, stay for the whole pie.

Address
5029 US-61
Perryville, MO 63775-7296
Hours
Mon – Thu11:00 AM – 9:00 PM
Fri – Sat11:00 AM – 10:00 PM
Sunday12:00 PM – 8:00 PM

Ready for a slice
you won't forget?

Call us to place your order or stop by on US-61. Your table is waiting.

(573) 547-7474 Email Us
Is this your business?This is my business